About StatEpigen

The objective of this resource is to integrate and comprehend the function of molecular genetic and epigenetic events to a pathology phenotype level. StatEpigen launches with a data collection focusing on colon cancer. Data on other pathologies are also available, and can be used for comparison with colon cancer phenotypes and subphenotypes.

The StatEpigen project aims at generating cancer epigenetic data in a computational format. The project is based on expert manual curation and annotation. StatEpigen does not replace other resources, but rather complements them by focusing on providing statistical information about molecular events involved in pathology. Many findings suggest that some genetic and epigenetic alterations are mutually correlated and may work synergistically. Therefore, StatEpigen also collects associations among molecular genetic / epigenetic events, correlated to specific pathology phenotypes, by looking at conditional frequencies of molecular events in samples distinguished by the presence or absence of other important biomolecular features. Read more

What you can do with StatEpigen

You will find two main types of data in StatEpigen:

1. Simple Frequencies of Molecular Events: The records give the molecular event and it's incidence, knowing the phenotype of the analysed samples: P(Event | Phenotype).

2. Conditional Frequencies of Molecular Events: Put the statistical information of molecular event incidence into its biological context by giving molecular event incidence in samples in which it is known that other important cancer molecular hallmarks are present or absent: P(Event2 | Event1, Phenotype).

Examples and more

Last update of the presentation: 28/10/11.
Content of the database is being continuously updated.

StatEpigen is continuously being updated with new data and undergoing quality contols & corrections

Genes:  728
Epigenetic Events:  318
Mutations:  150
Genetic Events:  579
All Simple Events:  5,768
All Condit. Events:  2,952
References:  339
Records carcinomas:  3,845
Records adenomas:  268
Records polyps:  230
Records ACF:  94